Gallbladder cancer: Is significant attention to this pathology justified?

The highest incidence rates of gallbladder cancer (GBC) are registered among the populations of South America (Bolivia: 7.6 per 100000 population), Asia (Bangladesh: 5.25 per 100000), and North Africa (Algeria: 2.65 per 100000). Recent studies demonstrate a significant association between GBC, cholelithiasis and extrahepatic gastrointestinal cancer, which allows for the development of a systemic approach to this problem and a more active search for pathophysiological predictors of such a relatio