Kaempferol attenuates diet-induced obesity and hepatic steatosis in C57BL/6J mice fed an Indian diet-mimicking regimen

BACKGROUND Metabolic dysfunction-associated steatotic liver disease (MASLD) ranges from simple steatosis to cirrhosis and liver cancer, with rising prevalence in India due to high fat, high sugar diets. Kaempferol, a generally recognized as safe-certified flavonoid found in fruits and vegetables with anti-inflammatory, antioxidant, and lipid-lowering properties. Despite its therapeutic promise, kaempferol’s efficacy remains unexplored in Indian diet-based obesity liver disease models. Developing