Paget’s disease of the nipple with occult ductal carcinoma in situ despite negative conventional imaging: A case report

BACKGROUND Mammary Paget’s disease, also known as Paget’s disease of the breast (PDB), is a rare malignancy of the nipple-areolar complex that is frequently associated with underlying ductal carcinoma in situ (DCIS) or invasive carcinoma. However, the underlying malignancy may remain occult on conventional imaging, potentially delaying diagnosis. CASE SUMMARY We report the case of a 75-year-old woman with a 2-year history of a persistent erythematous lesion of the right nipple, initially treated