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ZZenodo (CERN European Organization for Nuclear Research)10d ago

FORMULATION AND OPTIMIZATION OF KETOCONAZOLE LOADED ETHOSOMAL GEL FOR TOPICAL APPLICATION: IN VITRO & EX-VIVO CHARACTERIZATION

Dr. Ch. Saibabu*1, Bhulakshmi Kambhampati2, Palaparthi Lakshmi Vyshnavi2, Poojala Sravani2, Animireddy Meghana2, Narapusetti Varalakshmi2, Kothapalli Vijaya Lakshmi2, Kommu Sowjanya2, Kankanala Akash2, P. L. Hari2, Shaik Imran Ahmed2
The present study aimed to develop Ketoconazole -loaded ethosomal gel intended to be applied topically for treating skin infections. Ethosomes were prepared using the cold method. The formulation variables were optimize dusing[3] factorial designand Design Expert® software for analyzing the data statistically and graphically using response surfaceplots. Phospholipid (X1) and ethanol (X2) and propylene glycol (X3) were chosen as the independent variables, while the dependent variables comprised e
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Advancements in Transdermal Drug DeliveryPharmaceutical Science