Introduction: Laryngoscopy and endotracheal intubation induces significant sympathetic stress response, leading to tachycardia and hypertension which can be often deleterious, particularly in laparoscopic surgeries. Several pharmacological agents have been evaluated in order to reduce this response. Dexmedetomidine, a selective alpha 2-adrenergic agonist, and intravenous lignocaine have been shown to have some effects on the haemodynamic responses during surgery. Aim: To compare the effectivenes