Case Report: a three-stage treatment strategy combining immunotherapy with chemoradiotherapy for locally advanced esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC), a common malignant tumor with high incidence and mortality in China, remains challenging to treat, especially in advanced stages. Traditional definitive chemoradiotherapy (dCRT) has been the standard care for unresectable locally advanced ESCC but has shown limited long-term efficacy. Recent advances in immune checkpoint inhibitors (ICIs) have opened new avenues for enhancing treatment outcomes. This case report details a 62-year-old male with upper tho