Association of IL-6 and IL-17 with thyroid eye disease

Background Thyroid Eye Disease (TED) is the most common extrathyroidal manifestation of Graves’ disease. Interleukin-6 (IL-6) and interleukin-17 (IL-17) have been implicated in its pathogenesis, but individual study results remain inconsistent. However, existing findings on IL-6 and IL-17 levels in the serum or tears of TED patients remain inconsistent. Aim This meta-analysis aimed to statistically evaluate the level of IL-6 and IL-17 in patients with TED. Methods A systematic literature search