Comprehensive whole-genome characterization of SARS-CoV-2 strains in Jining China 2024–2025

Objective To characterize the whole-genome features and evolutionary variation patterns of severe acute respiratory syndrome coronavirus 2 circulating in Jining City during 2024–2025. Methods Whole-genome sequencing was performed on clinical specimens collected from SARS-CoV-2–infected cases in Jining City during 2024–2025 using next-generation sequencing technology. Phylogenetic and mutation analyses were conducted using standard bioinformatics tools. Results A total of 429 complete SARS-CoV-2