infectious-diseases

IntroductionDirect-acting antivirals (DAAs) have dramatically changed hepatitis C virus (HCV) treatment, by achieving high virological cure rates and a reduced percentage of adverse events compared with previous treatments. Despite this, long-term psychiatric and quality-of-life (QoL) outcomes after viral eradication remain insufficiently understood. This study provides an 80-month follow-up of a…

BackgroundCadmium(Cd) exposure is associated with anxiety, but mechanism-informed multi-target interventions are limited.MethodsWe profiled plasma proteomes by LC-MS/MS in a propensity-score-matched Cd-exposed cohort (25 anxious vs 25 non-anxious). Anxiety-associated proteins were used as seeds for reverse screening in TCMIP v2.0, followed by network integration, molecular docking, 100ns molecula…

Health workers responding to a rapidly spreading outbreak of a rare type of Ebola in eastern Congo face two kinds of threats.

Director general of World Health Organization urges neighbouring countries to take immediate action The World Health Organization has warned that the Ebola outbreak is outpacing response efforts and countries neighbouring the Democratic Republic of Congo (DRC) are at high risk from the disease. “We are urgently scaling up operations, but at the moment the epidemic is outpacing us,” said the WHO’s…

Doctors Still Struggle to Diagnose a Condition That Kills More Americans Than Stroke https://www.theatlantic.com/health/...telligence-diagnosing-early-detection/671755/ Each year in the United States, sepsis kills more than a quarter million ... Read more

Two other small British children who stayed at same hotel fell critically ill from same condition months earlier The travel company Tui is under scrutiny over its safety protocols after a British baby girl died from a gastric illness following a stay at an Egyptian hotel – the same resort where two other children were left critically ill from the same condition months earlier. Ariella Mann, one, …

There have been arson attacks on Ebola treatment centres in eastern Democratic Republic of the Congo, exposing the anger in a region beset by violence linked to armed rebel groups. Authorities say the number of suspected cases has passed 900. The World Health Organization has said the outbreak now poses a very high risk for DRC, but that the risk of the disease spreading globally is low Suspected…

Ever-growing influence of social media and AI means such ideas spreading at faster rates than before, experts say Hantavirus and Ebola outbreaks carry with them familiar attendants in the US: extreme conspiracy theories about a planned pandemic, or “plandemic”, designed to upend midterms elections or push new vaccines or any one of a myriad of wild ideas. Ebola, which the World Health Organizatio…

This study evaluated broth microdilution (BMD) and fluorescence PCR melting curve analysis (MeltPro MTB/PZA, targeting pncA mutations) for detecting pyrazinamide (PZA) resistance-associated mutations in rifampicin-resistant tuberculosis (RR-TB). PZA susceptibility was assessed in RR-TB isolates from patients at TB prevention and control institutions and at designated hospitals in Beijing. Whole-g…

Nature Immunology, Published online: 25 May 2026; doi:10.1038/s41590-026-02522-6 mRNA-based vaccines saved millions of lives during the COVID-19 pandemic, but they require frequent boosting and periodic updates to match emerging virus strains. We demonstrate that fungal glycans can function as adjuvants for mRNA-based vaccines, expanding the durability and breath of protection against several vir…

Experts say several crises combine to make this Ebola outbreak in eastern Congo, the scene of many such outbreaks over the years, especially difficult to contain.

An overview of sepsis symptoms, treatment, care, efforts to improve treatment, and prevention, in the wake of a NASCAR superstar's death.

Acta Pharmacologica Sinica, Published online: 25 May 2026; doi:10.1038/s41401-026-01829-2 Sirolimus potentiates oncolytic Virus M1 efficacy through tumor-selective augmentation of viral replication

Scientific Reports, Published online: 25 May 2026; doi:10.1038/s41598-026-54539-4 CBC-derived inflammatory indices predict adverse outcomes in geriatric emergency patients with acute infectious diarrhea: a MIMIC-IV analysis

Influenza A virus (IAV) continues to pose a substantial challenge to global health, not merely through primary viral pneumonia but largely due to lethal secondary bacterial complications. Pathogens such as Streptococcus pneumoniae, Staphylococcus aureus, and Haemophilus influenzae capitalize on the physiological “storm” induced by IAV, leading to significantly exacerbated morbidity. This review p…

BackgroundHuman papillomavirus 33 (HPV33) is among the five most prevalent HPV genotypes in China and is commonly involved in co-infections. However, the synergistic effects of specific genotype combinations on cervical carcinogenesis remain incompletely understood. This study aimed to characterize HPV33 co-infection patterns and their associated genetic variations in relation to cervical lesion …

A new review article is drawing attention to the growing global impact of human papillomavirus (HPV) and the rapid progress in vaccines and therapeutic strategies aimed at reducing the burden of cervical and non-cervical cancers.

A small clinical trial found that a single low-dose infusion of ketamine reduced exhaustion in patients with various chronic illnesses. The findings suggest fast-acting medications could eventually offer relief for people struggling with debilitating and persistent tiredness.

Congolese authorities announce that suspected Ebola cases in the country's east now exceed 900, including 119 deaths.