Infection-associated sTNFR1 elevation predicts post-transplant thrombotic microangiopathy in severe aplastic anemia
Ruiqing Zhou·Wenjian Mo·Yumiao Li·Ming Zhou·Shilin Xu·Xiangjun Liu·Wengen Chen·Yuping Zhang·S Q Wang·X W Chen
Background Transplant-associated thrombotic microangiopathy (TA-TMA) is a severe and potentially fatal complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Early identification of patients at risk is essential for timely intervention and improved outcomes. This study aimed to identify biomarkers capable of predicting the early risk of TA-TMA in patients with severe aplastic anemia (SAA) undergoing allo-HSCT. Methods In a prospective nested case–control study of