Advancements and challenges in the management of chronic inducible urticaria

Chronic inducible urticaria (CIndU) is a group of diseases characterized by recurrent wheals and/or angioedema induced by specific triggers. Research into its underlying mechanisms remains underdeveloped, historically lagging behind that of chronic spontaneous urticaria (CSU). The profound heterogeneity across CIndU subtypes presents a central challenge, translating into limited and variable efficacy of conventional therapies, including second-generation H1-antihistamines and omalizumab, highlig