Revealing physical properties of gastric adenocarcinoma cells with two distinct morphologies linking to preferential cellular migration and proliferation

Mechanobiology has played significant roles in guiding and regulating cellular activities, such as morphogenesis, organogenesis, wound healing. Inter-/intracellular force or stiffness as an engine induced cell to reshape their morphologies leading to distinct cell functionalization. Therefore, biophysical changes (roughness, stiffness) of cell membrane are highly correlated to the varies in cell morphologies, specifically shape. While studying on the relationship among cell shapes, cell life act