Charge‐Engineered COFs for Biointegrated Memristor Nerves

Restoring motor function after neurological injury requires artificial neural interfaces that emulate biological rate coding with low power and stability. Here, we present a molecular-level strategy to engineer covalent organic frameworks (COFs) for biointegrated memristors as artificial efferent nerves. Leveraging intrinsic porosity and chemical tunability, we modulate ionic transport and memristive dynamics via charged group functionalization. We synthesize positively and negatively charged CO