Alicyclobacillus acidoterrestris is a type of contaminating bacteria that can cause the spoilage of juice. To develop a nonthermal control method, lysozyme-modified copper phosphate nanoflowers (Ly@Cu3(PO4)2 NFs) were fabricated. The microstructure and composition of the hybrids were characterized, and the antibacterial performance was further evaluated. Antibacterial results exhibited that Ly@Cu3(PO4)2 NFs possessed effect