Localized Temperature Monitoring in Mouse Brain during Light Delivery via a Non‐Planar Tapered Fiber‐Integrated µRTD Sensor
Antonio Balena·Ferruccio Pisanello·Barbara Spagnolo·Alberto Bramati·Massimo De Vittorio·Muhammad Fayyaz Kashif·Marco Bianco
ABSTRACT Monitoring local brain temperature with high spatial precision is essential to understanding neurophysiological processes and managing the side effects of optical neuromodulation techniques. We present a novel multifunctional neural interface integrating a microscale resistance temperature detector (µRTD) onto the curved surface of a tapered optical fiber (TF), enabling co‐localized light delivery and thermal sensing with minimal footprint. The µRTD, patterned via an unconventional two‐