Revealing causal associations of 91 inflammatory protein factors with endocarditis: Insights from genome-wide association study

Inflammatory protein factors play key roles in the pathophysiology of endocarditis. Using publicly available population-level databases, this study investigates their potential causal relationships with endocarditis to identify candidate biomarkers for precise diagnosis and therapy. We performed 2-sample Mendelian randomization to investigate causal relationships between endocarditis and 91 circulating inflammatory proteins. Summary genome-wide association studies data for endocarditis were deri