Genetic associations of variants in 10 glaucoma-related genes with POAG risk and structural phenotypes in Korean subjects

While a few studies have reported on single nucleotide polymorphisms associated with glaucoma in the Korean population, comprehensive data on genotype-phenotype correlations across multiple candidate genes are lacking. This study aimed to investigate the associations of variants in 10 candidate genes (CDKN2B, SIX1, SIX6, SCYL1, CHEK2, ATOH7, DCLK1, RERE, CDC7, and CARD10) with primary open-angle glaucoma (POAG) susceptibility and structural phenotypic features. We employed a 2-stage study design