Statistics of natural scenes shape contextual modulation in the visual cortex
Jiakun Fu·Katrin Franke·Zhuokun Ding·Nikos Karantzas·Kayla Ponder·Jacob Reimer·Rachel Froebe·Lydia Ntanavara·Luca Baroni·Fabian H. Sinz·Andreas S. Tolias·Suhas Shrinivasan·Taliah Muhammad·Ralf M. Haefner·Dat Tran·Xaq Pitkow·Konstantin F. Willeke·Eric Wang·Paweł A. Pierzchlewicz·Zhiwei Ding·Paul G. Fahey·Saumil Patel·Stelios Papadopoulos·Alexander S. Ecker·Ján Antolík
Vision is context dependent, with neuronal responses shaped not only by local features but also by surrounding visual input. While classical studies, using grating stimuli, show that iso-oriented surrounds suppress responses more than orthogonal surrounds, the role of contextual modulation under natural stimulus conditions remains less clear. Using recordings from mouse primary visual cortex (V1), we trained convolutional neural network models to predict neuronal responses to natural images and