A Dual Machine Learning Framework for Automated ASPECTS Scoring and Treatment Eligibility in Acute Ischemic Stroke

The Alberta Stroke Program Early CT Score (ASPECTS) is a standardized method to assess early ischemic changes in the middle cerebral artery (MCA) territory on Non-contrast computed tomography (NCCT) scans. It plays a critical role in acute stroke management by guiding clinicians identify candidates for intravenous thrombolysis or mechanical thrombectomy based on the extent of ischemic damage. However, manual ASPECTS evaluation suffers from inter-observer variability and depends heavily on clinic