Impact of fat mass and obesity-associated (FTO) gene variants on adult obesity and overweight: a comprehensive meta-analysis
Maryam Eghbali·Sara Cheraghi·Tofigh Mobaderi·Neda Hatami·Mahta Iranmanesh·Omolbanin Asadi Ghadikolaei
Obesity has become one of the most common disorders in the world and causes a significant public health challenge. Genome-wide association studies (GWAS) have identified variants within the FTO gene as an important genetic risk factor for obesity. This study evaluates the associations between FTO gene variants and the risk of obesity in adults. In this study, we conducted a comprehensive search across PubMed, Scopus, and Web of Science, covering literature up to January 2025. Subsequently, a met