Representational similarity modulates neural and behavioral signatures of novelty

Novelty signals in the brain drive exploration and learning. While the perceived novelty of a stimulus is known to depend on previous experience, it remains elusive how generalization between familiar and novel stimuli impacts novelty computation. Specifically, existing models of novelty computation fail to account for the effects of stimulus similarities that are abundant in naturalistic tasks. Here, we present a biologically plausible model that captures how stimulus similarities modulate nove