PPhytomedicine3/17/2026

Si-Ni-San alleviates depressive-like behaviors in adolescent male mice by restoring DRN-NAc serotonergic circuit function and 5-HT4R-dependent synaptic plasticity

Yue Wang·Jinlan Zhao·Chuxin Huang·Yafei Shi·Lihong Ye·Huixian Liang·Rong Zhang·Zhongqiu Liu·Shasha Bai·Di Deng·Zuyi Liu·Lei Yang·Lin An·Yao Xuan·Jing Wu

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Neurogenesis and neuroplasticity mechanismsDevelopmental Neuroscience