Repurposing existing drugs for cancer stem cell-directed therapy

Cancer stem cells (CSCs) pose a significant challenge in tumor treatment due to their ability to remain quiescent during therapy and thus evade chemo- and radio-therapy. In addition, their ability to initiate tumor formation from a single cell is another essential factor to consider when developing a strategy to eradicate CSCs. Given that developing novel drugs is a time-consuming and costly process, drug repurposing has become an increasingly utilized and appealing alternative in recent researc