The Comprehensive Systematic Review of Association of Posterior Capsular Opacification (PCO) to IOL Material and Design

Introduction: Posterior capsule opacification (PCO) remains the most common long-term complication of modern cataract surgery, leading to visual degradation and necessitating Nd:YAG laser capsulotomy. The risk of PCO is influenced by intraocular lens (IOL) characteristics, including material, optic edge design, and haptic configuration. However, the relative importance of these factors and potential interactions remain a subject of extensive research with sometimes conflicting findings. Methods: