parkinsons

A new study led by researchers from VIB and KU Leuven shows that Parkinson's disease can be divided into distinct subtypes, helping explain why a single treatment does not work for all patients.

A new study led by researchers from VIB and KU Leuven shows that Parkinson's disease can be divided into distinct subtypes, helping explain why a single treatment does not work for all patients. Using an machine-learning-driven analysis, the team identified two main groups and five subgroups of the disease, marking an important step toward more personalized therapies. The findings were recently p…

Scientists have identified a protective brain pathway that may help slow the progression of Parkinson's disease by strengthening the brain's own dopamine‑producing neurons, but the positive effect was only observed in females.

The 18th BioVaria brought a record 360 participants from across the international life-science community to Munich. As Europe's leading platform for commercially promising academic innovations, BioVaria connects researchers, entrepreneurs, investors, and industry partners - accelerating the path fro...

Parkinson’s disease is a condition that slowly affects the brain and makes movement harder over time. People with Parkinson’s may notice shaking, stiffness, and trouble with balance. These symptoms happen because certain brain cells stop working properly. These cells are responsible for making dopamine, a chemical that helps control smooth movement. Most current treatments help […] The post Exper…

Parkinson’s disease is a long-term brain condition that affects movement, thinking, and daily life. It often develops slowly over many years. People with Parkinson’s may notice shaking, stiffness, slow movement, and trouble with balance. These symptoms happen because certain brain cells are damaged or lost over time. One of the key systems affected in Parkinson’s […] The post Scientists find way …

Researchers at UTHealth Houston have been awarded a three-year, $7.8 million grant from the Aligning Science Across Parkinson's initiative to support projects that will help better understand how Parkinson's disease occurs in the brain.

A new long-term study has found that many people with Parkinson’s disease are already using mental health medications even before they are diagnosed. The research suggests that symptoms affecting mood, sleep, and thinking may begin earlier than most people realize, long before the well-known movement problems appear. Parkinson’s disease is a condition that affects the […] The post Hidden symptoms…

A large study using wearable data from nearly 100,000 people suggests that lower activity levels do not cause Parkinson’s but are an early sign of the disease – raising the possibility of detecting it years earlier and intervening sooner.

As the flies aged, they developed Parkinson’s-like symptoms – including impaired movement and loss of brain cells – mirroring key aspects of disease progression seen in humans. Using large-scale genetic screening made possible by the fruit fly model, the researchers systematically identified genes involved in α-synuclein-induced toxicity. Among these, the gene mino stood out for […]

- Rebecca King Crews and her husband Terry Crews shared her diagnosis and decision to have focused ultrasound treatment. - She plans to have the other side of her brain treated in the coming months and calls the technology “the new frontier of medicine.” Rebecca King Crews, a singer and fashion designer, first noticed concerning numbness and coordination symptoms in 2012, which were initially dis…

What is Parkinson’s disease? Parkinson’s disease is a progressive movement disorder. Inside the brain, cells that produce dopamine, a brain chemical that helps control movement, start dying early. “We don’t know exactly what causes Parkinson’s disease, but several factors may contribute, such as aging, environmental exposures and genetics,” De Jesus said. Most patients are diagnosed in their 60s,…

Parkinson’s disease is a condition that affects the brain and mainly changes how a person moves. It develops slowly over time and usually gets worse as the years go by. Because it starts gradually, many people do not notice the early signs at first. These signs can be mild and different from person to person, […] The post Early signs of Parkinson’s disease you need to watch out appeared first on …

Parkinson’s disease is a long-term brain condition that affects how people move. It usually develops slowly and is most common in older adults. Many people with Parkinson’s notice shaking in their hands, stiffness in their muscles, and slower movement. These symptoms can make daily life more difficult over time. For many years, scientists have believed […] The post Why Parkinson’s tremor may not …

Scientists at Chalmers University of Technology in Sweden have identified biological markers that appear at the very beginning of Parkinson’s disease, before extensive damage occurs in the brain. These early changes leave measurable traces in the blood, but only during a limited timeframe. The findings reveal a brief but important opportunity for both early diagnosis [...]

Scientists have discovered how a toxic protein drains brain energy in Parkinson’s and how to stop it. Roughly 1 million people in the United States are living with Parkinson’s disease, and about 90,000 new cases are identified each year, according to the Parkinson’s Foundation. The condition is a progressive brain disorder that slowly destroys cells [...]

Deep inside the brain’s dopamine-producing cells, a toxic encounter is playing out. Alpha-synuclein, the protein that clumps into the hallmark tangles of Parkinson’s disease, isn’t just piling up. It’s hijacking a crucial cellular guardian. The target is ClpP, a protein that normally keeps the cell’s energy factories running smoothly. When alpha-synuclein latches onto ClpP through a specific dock…

Scientists have identified the role of an ion channel that plays a key part in how cells break down and recycle components, a discovery that could open the door to new treatment strategies for Parkinson’s disease. Washbowls, bathtubs, and sinks include an overflow that keeps water from spilling out. Researchers now report that cells appear [...]

Northwestern Medicine scientists have discovered that targeting neuronal signaling controlling aberrant learning in the striatum may improve the efficacy of a first-line therapy for Parkinson’s disease and has the potential to reduce therapy-related side effects, according to a recent study published in Science Advances. The post Targeting Aberrant Learning May Improve Parkinson’s Treatment appea…

FAU researchers shine a spotlight on an important risk factor for Parkinson’s and Gaucher’s disease In Germany, approximately 400,000 people suffer from Parkinson’s, and numbers are on the rise. Using an electron microscope, a team of researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Uniklinikum Erlangen (UKER) were able to make a major risk factor for the […]