parkinson-s-disease

Using CHARLS data from 2011 to 2020, researchers found that sleep duration and self-reported sleep quality were associated with Parkinson’s disease risk in middle-aged and older Chinese adults. Short sleep was linked to higher PD risk, while age-specific patterns suggested a linear association in adults aged ≤60 years and a U-shaped relationship in those aged […]

* New study from University Hospitals, Case Western Reserve University, and the Cleveland VA identifies a potential new treatment strategy for Parkinson's disease. * Scientists found that blocking the enzyme 15-PGDH protected brain cells and improved outcomes in multiple preclinical models of Parkinson's disease. * The findings suggest that drugs already being developed for other uses could poten…

BackgroundCardiovascular dysautonomia is a debilitating non-motor symptom of Parkinson’s disease (PD) that limits exercise capacity and neurorehabilitation outcomes. Transcutaneous auricular vagus nerve stimulation (taVNS) is an emerging non-invasive neuromodulatory therapy that modulates cardiovascular activity and could potentially serve as an adjunct to exercise, yet its physiological effects …

Parkinson's disease occurs when nerve cells in the brain that are responsible for producing dopamine, die or become impaired. Dopamine allows the body's muscles to move smoothly, and without it, a person slowly loses control of their movements. While the current treatment options for Parkinson's help to replenish a patient's dopamine levels, they are often only a short-term fix and can have sever…