osteoporosis

Scientific Reports, Published online: 22 May 2026; doi:10.1038/s41598-026-54616-8 Association between body composition, knee synovial effusion, and serum glutamate in middle-aged women with knee osteoarthritis: a cross-sectional study

ObjectivesOsteoporosis is a systemic skeletal disease characterized by excessive osteoclast-mediated bone resorption. This study aimed to evaluate the therapeutic potential of 5-methoxyresorcinol (MR) in osteoporosis and to clarify its underlying mechanisms.MethodsNetwork pharmacology analysis was performed to identify shared targets between MR and osteoporosis. In vitro experiments using bone ma…

Increasing bone density in patients with a rare genetic condition that causes bones to break easily does not prevent fractures, a large clinical trial has found.

Osteoporosis, which is highly prevalent in postmenopausal women, has long been associated with an increased risk of fractures.

Osteoporosis, a common skeletal disorder, is marked by reduced bone mass and deterioration of bone microarchitecture, making bones more porous and prone to fractures.

BackgroundPostmenopausal osteoporosis (PMO) is driven by estrogen deficiency, enhanced osteoclastic activity, impaired osteoblast function, and persistent inflammatory signaling. Eucommia ulmoides extract (EUE) and soy isoflavones (Isf) are known to possess phytoestrogenic and anti—inflammatory properties, but their combined molecular effects on PMO remain unclear.MethodsAn ovariectomy—induced PM…

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent osteoblasts in inactive bone surfaces return to an active state.

A study in mice traced the loss of cartilage that accompanies aging to a single...

A little-known receptor may reshape how scientists approach bone loss. Scientists at Leipzig University have identified a little-studied receptor that could open the door to a new way of treating osteoporosis, a disease that weakens bones and raises the risk of fractures. The condition affects about six million people in Germany, most of them women, [...]

Scientific Reports, Published online: 19 April 2026; doi:10.1038/s41598-026-48603-2 Comparative outcomes of osteoporotic fracture management between tertiary hospitals and fracture liaison services in Malaysia

Osteoporosis is often called a silent disease because it develops slowly and without clear symptoms. Over time, bones become weaker and more likely to break. Many people only discover the problem after a fracture occurs. As people age, bone density naturally decreases. This is especially true for women after menopause, when hormonal changes speed up […] The post New finding may lead to a cure for…

Research points to a key bone-strengthening mechanism at work in the body, which could be...

Screening for osteoporosis is recommended at age 65, but experts say women should be proactive about bone health long before that.

GRAND RAPIDS, Mich. (April 19, 2023) — Van Andel Institute scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer […] Van Andel Institute - Van Andel Institute transforms human health through groundbreaking biomedical research and cutting-edge science education.

Osteoporosis is the most common chronic metabolic bone disease and it often goes undiagnosed and undetected until you unexpectedly fracture a bone. The disease affects men and women and its occurrence is rising. The costs of preventing or not treating osteoporosis are high. Patients often experience extreme complications after one year of major fractures as […] The post 10 Ways to Support Clients…

One of the biggest challenges women face after menopause due to hormonal changes is osteoporosis – a medical condition where bones become too brittle, weak and fragile. A little physical activity weekly can, however, go a long way towards protecting women’s bones at older age. Read more Continue reading →

While day-to-day physical activities such as walking, housework and shopping may be good for your heart, they don’t do much for your bones, according to a Johns Hopkins study. The new report, published in the November issue of the Journal of Internal Medicine, found that neither light-intensity activities nor aerobic fitness level contributed to bone health, contrasting previous studies suggestin…