alzheimers
Alzheimer’s Research UK says patients at risk of being left behind as lack of formal or accurate diagnoses closes door to trials People with Alzheimer’s disease are missing out on experimental treatments because they are not diagnosed early or accurately enough to be enrolled in clinical trials, a UK charity has said. Trials of Alzheimer’s drugs reached a record high this year, according to data …

Alzheimer’s disease is one of the most serious health challenges in the world today. It affects more than 55 million people, and that number is expected to grow quickly in the coming years. For a long time, scientists believed that Alzheimer’s begins in the brain, caused by the slow buildup of harmful proteins that damage […] The post Could Alzheimer’s start in the gut? appeared first on Knowridg…
Alzheimer’s disease is one of the most serious brain conditions in the world today. It slowly damages memory, thinking ability, and daily functioning. Many people know that Alzheimer’s is linked to a buildup of a sticky protein called amyloid-beta in the brain. This protein forms clumps, often called plaques, that interfere with how brain cells […] The post A hidden brain cleaning system may hold…
Researchers have identified a new potential weapon against Alzheimer’s: blocking a protein called PTP1B. In mice, this approach boosted memory and helped brain immune cells clear harmful plaque buildup. Since PTP1B is also linked to diabetes and obesity—both risk factors for Alzheimer’s—it could offer a broader treatment strategy.
The list of potential benefits of GLP-1 drugs is only getting longer, with a new...
Alzheimer’s disease is often linked with memory loss, but the earliest signs can be much more subtle. One of the first changes many people experience is a reduced ability to smell. This may seem like a small issue, but it can be an early signal that something is happening in the brain. For many years, […] The post Why smell loss happens first in Alzheimer’s disease appeared first on Knowridge Sci…
The brain changes associated with Alzheimer's usually lead to a severe loss of memory and...

Mass General Brigham researchers used long-term data and a blood test for the biomarker pTau217 to identify the earliest signs of Alzheimer’s disease in cognitively healthy adults. A team of investigators at Mass General Brigham reports that a blood test measuring plasma phosphorylated tau 217 (pTau217), a biomarker linked to Alzheimer’s disease, can forecast changes [...]
For many years, scientists believed that a protein called amyloid beta was the main cause of Alzheimer’s disease. This protein builds up in the brain long before symptoms appear. Because of this, many treatments have focused on removing amyloid in the hope of slowing the disease. However, a new review of research suggests that this […] The post Why clearing amyloid may not help Alzheimer’s patien…
Alzheimer’s disease is one of the most feared illnesses in the world. It slowly damages memory, thinking, and daily functioning. For many years, scientists have focused on a protein in the brain called amyloid beta. People with Alzheimer’s often have high levels of this protein, which forms sticky clumps in the brain. Because of this, […] The post Do Alzheimer’s anti-amyloid drugs really work? ap…
For many years, Alzheimer’s disease has been one of the biggest challenges in medicine. It slowly damages memory, thinking, and daily life, affecting millions of older adults around the world. Scientists have spent decades searching for treatments that can slow or stop the disease, and for a time, a group of drugs targeting a substance […] The post Alzheimer’s ‘breakthrough’ drugs face doubts aft…
Despite reducing amyloid plaques, antibody treatments for Alzheimer's fail to improve cognition, highlighting critical gaps in current therapeutic approaches.
Analysis of over 600 post-mortem brains reveals ATP depletion as key in Alzheimer's-related ferroptosis, pointing to new treatments. The post ATP depletion the key driver of ferroptosis in Alzheimer’s brains appeared first on Advanced Science News .
Researchers used a microscopic model of human nerves and muscles to show that Alzheimer's disease directly damages peripheral nerves. This physical damage happens independently of cognitive decline and does not improve with standard medications for the illness.
For decades, scientists have concentrated on what now looks to be a blind alley.
With a NOK 40 million (approx. €3.5 million) grant, Professor Srdjan Djurovic at the University of Oslo aims to identify early blood-based biomarkers that can predict who is at increased risk of developing Alzheimer's disease.
Losing your sense of smell might signal Alzheimer’s far earlier than expected. Scientists found that immune cells in the brain actively destroy smell-related nerve fibers after detecting abnormal signals on their surfaces. This damage begins in early stages of the disease, well before cognitive decline. The discovery could help identify at-risk patients sooner and improve treatment timing.
New research has linked levels of vitamin D in midlife with toxic tangles of tau...
A new study finds that combining the current medications for Alzheimer's disease with small molecules derived from micronutrients found in grapes, berries, peanuts and turmeric is a safer and more effective way to treat the disease.
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