Oral Oncology

In 568 patients, including 343 in the derivation and 225 in the validation cohort, the mean age was 65 with 228 (40%) patients being frail and 259 (46%) sarcopenic. Treatment intolerance occurred in 270 (48%) patients. Independent predictors of treatment intolerance included low cervical paraspinal SMI, elevated Risk Analysis Index (RAI), reduced high-to-low attenuation SMI ratio and obesity. Sar…

• Authors highlight an initiative to reduce tracheostomies for free flap cases. • Tracheostomy rates dropped from 92.6% to 42.7% (411 patients, pre- vs. post-2018) • Post-2018, tracheotomy risk factors included primary site and advanced nodes. • No increase in airway or flap failure complications rates in patients without tracheostomies after initiative began. In 2018, an initiative at the author…

Our technique for in-office secondary TEP via TNE and the Seldinger technique is feasible, effective, and well tolerated by patients.

Integrating routine indicators-LSMI, age, and LDH-provides a practical tool for identify patients who are likely to derive substantial benefit or experience irAE-related harm from ICIs, enabling optimized patient selection beyond PD-L1 expression in daily clinical practice.

Functional impairments were the most consistently patient-reported symptoms following maxillary free flap reconstruction. There is a need for well-designed, adequately powered studies that identify patient- and treatment-related predictors of HRQOL and compare different treatment options. Such insights could improve preoperative counseling and support shared decision-making, ultimately enabling m…

Both smoking and drinking were associated with a higher risk of OPC mortality, particularly among those with fewer teeth.