We thank Biswas and colleagues for their thoughtful comments regarding our study, Abnormal myocardial perfusion reserve and myocardial infarction determine cardiovascular outcomes in type 2 diabetes mellitus.1 Biswas et al. raise three principal points. Noor Sharrack (Writing—review & editing [supporting]), Gaurav S. Gulsin (Writing—review & editing [supporting]), and Sven Plein (Writing—original draft [lead]) No new data were generated or analysed in support of this research.