PURPOSE: Good quality information on family planning is essential for people with multiple sclerosis (pwMS), yet how they receive or seek information about family planning to inform reproductive decision-making is unknown. This cohort study aimed to understand the impact of MS on family planning experiences and identify how pwMS prefer to receive information informing reproductive decisions. MATERIALS AND METHODS: A cross-sectional study was conducted in 2023 involving participants from the Australian Multiple Sclerosis Longitudinal Study. Data were analysed using descriptive methods. RESULTS: 270 pwMS completed the survey with a mean age of 42.7 years. Nearly half (44.0%) reported MS having an impact on reproductive planning decisions; 14.7% indicated MS made them decide against having children. A considerable number of participants indicated not receiving or seeking information related to family planning topics. When information was sought, the main source for all family planning topics was the neurologist. 50.8% believed that family planning should first be discussed at MS diagnosis, with preferred information sources being MS specialists, written handouts and internet. CONCLUSIONS: MS affects family planning decisions. Early discussions, ideally at the time of diagnosis, are preferred, and opportunities to improve provision of family planning information for pwMS exist.