Abstract Using a combination of computational and experimental methods, the corrosion protection effectiveness provided by cyclobenzaprine (CBA) for carbon steel (CS) in a 1.0 M hydrochloric acid solution was systematically examined. The corrosion protection efficiency and electrochemical behavior of CS with and without different concentrations of CBA were assessed using gravimetric measurements, polarization studies, impedance measurements, and the evaluation of the open circuit potential. The