Development, previously oriented toward economic growth, has now shifted toward human development. The Human Development Index (HDI) is used as an indicator to measure human welfare through the dimensions of education, health, and purchasing power. This study aims to analyze the influence of government spending in the health sector, government spending in the education sector, and per capita expenditure on the HDI in South Sulawesi Province for the period 2009–2023. This study uses a quantitativ