Liquid or soft-gel levothyroxine vs tablet levothyroxine in athyreotic adults after total thyroidectomy: Systematic review and meta-analysis
Muhammad Farhan·Ayoola Awosika·Mohammed Al-Hadi Naseer Obais·Hassan Taslimi·Maira Hanif·Kawish Khalid·Ali Qaqour·Juman Waisi·Hafsa Khalid·Aalaa Hasan Abdulla Abbas Husain·Ruba hammouda·Safi U. Khan·Bhumi Daishik Patel·Nana Sardarova·Tirath Patel
BACKGROUND Achieving stable thyroid hormone replacement after total thyroidectomy is challenging owing to the variability in levothyroxine (LT4) absorption. Newer liquid and soft-gel formulations may offer improved bioavailability compared to conventional tablets, but their benefits in thyroidectomized patients remain uncertain. AIM To compare the effectiveness of liquid and soft-gel LT4 with tablet LT4 in athyreotic adults following total thyroidectomy. METHODS A systematic review and meta-anal