Letter to the Editor: Characteristics of peripheral blood lymphocyte subpopulations in acute-on-chronic liver failure: A call for further exploration

A recent study by Peng et al , published in the recent issue of World Journal of Gastroenterology , investigated the characteristics of peripheral blood lymphocyte subsets (PBLSs) and immune reconstitution patterns in patients with acute-on-chronic liver failure (ACLF) following liver transplantation. The findings revealed significant PBLS deficiencies in ACLF patients, with reduced natural killer (NK) cell counts potentially contributing to the progression of compensated cirrhosis to liver fail