Phenotypic and genotypic characterization of clinical plasmid-mediated quinolone resistance (PMQR) and extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales in two healthcare facilities in Douala, Cameroon
Giresse Wilfried Guemkam·Raspail Carrel Founou·Patrice Landry Koudoum·Megane Daina Foueyem·Brice Davy Dimani·Medi Sike Christiane·Michel Noubom·Luria Leslie Founou
The emergence and escalation of antibiotic resistance in community and hospital settings remain a major public health concern worldwide. The co-occurrence of fluoroquinolone resistance in extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E), which are responsible for life-threatening infectious diseases, poses a critical threat, leading to increase therapeutic costs, prolonged hospital stays, and higher mortality rates, particularly in low- and middle-income countries (LMICs) like C