Advances in quantitative ultrasound for metabolic dysfunction-associated steatotic liver disease diagnosis

Metabolic dysfunction–associated steatotic liver disease (MASLD) is increasing worldwide, underscoring the need for noninvasive, repeatable biomarkers for accurate clinical stratification. This review synthesizes recent advances in quantitative ultrasound (QUS) for MASLD phenotyping, spanning attenuation-based metrics (e.g., controlled attenuation parameter, tissue attenuation imaging, ultrasound-guided attenuation parameter), shear-wave elastography, backscatter analysis, sound-speed imaging, a