Evolutionary trends and genetic determinants of third-generation cephalosporin resistance in Escherichia coli from Korean livestock: a 14-year longitudinal study, 2010–2023
Ji-In Kim·Suk-Kyung Lim·Md. Sekendar Ali·Bo‐Youn Moon·Hee-Seung Kang·Ha-Young Kim·Yu-Jeong Hwang·Yeon-Hee Lee·Min Young Kim·Jae‐Myung Kim·Tatsuya Unno·Ji-Hyun Choi
The emergence of third-generation cephalosporin-resistant Escherichia coli in livestock is a critical public health concern due to its potential transmission to humans via the food chain. This study investigated the 14-year longitudinal trends (2010–2023) of third-generation cephalosporin resistance, its genetic determinants, and phenotypic characteristics in E. coli isolated from various livestock species in South Korea. Resistance was significantly higher in chickens and pigs than in cattle, w