Pediatric cancer, while relatively rare, is the number one cause of death by disease in children in the US. Five-year relative survival for pediatric cancers has improved overall to over 80%, but the same gains have not been observed among all populations, with noted disparities by race, ethnicity, and socioeconomic status. This dissertation uses data from the Louisiana Tumor Registry and Iowa Cancer Registry in a population-based longitudinal analysis of all children aged 0-19 at diagnosis from