Sarcopenia in Kidney Transplantation: Bridging Pathophysiology to Patient-Centered Care
Anna Pisacreta·Carlo Alfieri·Lara Caldiroli·Margherita Di Naro·Francesco Pesce·Anna Amici·Anna Regalia·Simona Verdesca·Silvia Malvica·Giuseppe Grandaliano·Giuseppe Castellano·Paolo Molinari
Sarcopenia, defined as the progressive loss of skeletal muscle mass and strength, is increasingly recognized as a significant concern in patients with chronic kidney disease (CKD) and particularly in kidney transplant recipients (KTx-ps). This review explores the complex interplay of pathophysiological mechanisms, prevalence, and management strategies of sarcopenia in the context of kidney transplantation. CKD contributes to sarcopenia through systemic inflammation, malnutrition, uremic toxin ac