The Incremental Value of Copeptin for the Early Rule-Out of Non-ST Elevation Myocardial Infarction in the Emergency Department
Sofia Bezati·J Parissis·Vasiliki Bistola·Dionysis Matsiras·Estela Kiouri·Lambros Markos·Ioannis Ventoulis·Effie Polyzogopoulou·Christos Verras
Background/Objectives: Copeptin, a marker of endogenous stress, has been used for the early detection of non-ST elevation myocardial infarction (NSTEMI) in combination with conventional cardiac troponin. However, its incremental diagnostic value, when combined with high-sensitivity troponin, is not well defined. This study seeks to assess the diagnostic performance for NSTEMI of a Dual Marker Strategy (DMS) [copeptin and high-sensitivity cardiac troponin T (hs-cTnT)] measured upon presentation t