Exercise in acute and subacute hypoxic conditions: physiological responses affecting oxygen delivery and their applications to human health

Exercise at altitude is performed by a spectrum of individuals ranging from healthy to those with cardiovascular and pulmonary diseases. Reduced atmospheric oxygen pressure at increased altitude reduces oxygen availability and poses unique challenges during exercise. This review explores the physiological responses to exercise under acute and subacute exposure to hypoxia within the autonomic, pulmonary, cardiovascular and haematologic systems. In response to acutely reduced arterial pressure of