Integrated bioinformatics-based identification of shared immune-related biomarkers in hepatocellular carcinoma and major depressive disorder

Hepatocellular carcinoma (HCC) and major depressive disorder (MDD) are characterized by shared pathophysiological mechanisms. However, the specific molecular indicators and the fundamental biological pathways driving this connection have yet to be fully elucidated. This study aims to identify immune-related molecular signatures shared by HCC and MDD using a systems biology approach and to evaluate their potential prognostic and immune-related relevance. By integrating MDD transcriptomic data fro