Early-Onset Metastatic Colorectal Adenocarcinoma Incidence and Survival Among Patients Younger Than 50 Years
Anne-Sophie Woronoff·François Ghiringhelli·Jean-Baptiste Nousbaum·Arnaud Alves·Guy Launoy·Emmanuel Désandes·Florence Molinié·Anne‐Marie Bouvier·French Network of Cancer Registries (FRANCIM)·Isabelle Baldi·Simona Bara·Véronique Bouvier·Emmanuel Chirpaz·Jacqueline Clavel·Gaëlle Coureau·Anne Cowppli-Bony·Sandrine Dabakuyo-Yonli·Laëtitia Daubisse‐Marliac·Patricia Delafosse·Jacqueline Deloumeaux·Kinan Drak Alsibai·Pascale Grosclaude·Adrien Guilloteau·Karima Hammas·Florent Huré·Clarisse Joachim·Brigitte Lacour·B. Lapôtre‐Ledoux·Marc Maynadié·Alain Monnereau·Sandrine Plouvier·Claire Poulalhon·Camille Pouchieu·Claire Schvartz·Arnaud Seigneurin·Xavier Troussard·Thomas Systchenko·Brigitte Trétarre·Michel Velten·Valérie Jooste·Nicolas Vigneron
In this cohort study, the incidence of EO mADC increased mainly among patients with multiple metastatic sites and those with peritoneum rather than liver or lung involvement. Net survival improved over time except for peritoneal involvement. These results suggest that intensive treatment is needed for young adults with EO mADC when the peritoneum is involved.