Understanding the Antihyperglycemic Activity of Annona cherimola Leaves. An Edible and Medicinal Plant in Mexico: In Vivo and Ex-Vivo Studies
Fernando Calzada·Elizabeth Barbosa·Jessica Elena Mendieta-Wejebe·Miguel Valdes·Claudia Velázquez·Jesica Ramírez-Santos·Yoseth L. Ruedaflores
Annona cherimola is a plant species widely used in Mexican traditional medicine, particularly in the management of diabetes. This study aimed to investigate the antihyperglycemic properties of the petroleum ether extract of A. cherimola leaves (PEEAcL), as well as to evaluate their effects on glycated hemoglobin and toxicity. In addition, the work was directed to determine its potential as an SGLT-1 and α-glucosidase inhibitor. The effect as a potential SGLT-1 and α-glucosidase inhibitor of PEEA