Mapping fast tissue dynamics with long camera exposures via intensity modulation

Measuring fast dynamic processes with dynamic light scattering over wide fields of view is critical for applications ranging from blood flow imaging to characterizing complex fluids, yet is often limited by the need for expensive, high frame rate cameras. Here, we introduce sinusoidal intensity modulation speckle imaging (SIMSI), a technique that overcomes this hardware limitation by encoding information about fast dynamics into images captured with long camera exposures. Within each exposure, w