Efficacy and safety of regional blocks and multimodal analgesia in psychiatric patients at risk of opioid misuse: A systematic review

BACKGROUND Patients with psychiatric diagnoses who are subjected to surgical treatments are at risk of abusing and becoming dependent on opioids, which requires alternate measures to manage pain. One might expect that regional blocks and multimodal analgesia can be effective solutions to minimizing opioid exposure without failing to treat pain somehow in the perioperative period. AIM To determine the efficacy and safety of regional blocks and multimodal analgesia in patients with psychiatric dis