Infratentorial cerebral microbleeds and brain age gap in stroke patients: a cross-sectional neuroimaging study
Raghav Pallapothu·Chris Rorden·Roger Newman‐Norlund·Sriya Pallapothu·Pranesh Rajesh Kannan·Sai Kanha Kummari·John Absher·Suneel Kudaravalli
Abstract Stroke survivors often face long-term cognitive and motor deficits. Brain age gap (BAG), the difference between chronological age and age estimated based on MRI data, has emerged as a biomarker for neurodegeneration. While prior work links BAG to stroke outcomes, the relationship between BAG and cerebral microbleeds (CMBs), particularly infratentorial CMBs common in hypertensive arteriopathy, remains unclear. The sensorimotor network (SMN) is highly susceptible to both direct and remote