Cost-effectiveness of latent tuberculosis infection testing and preventive treatment among TB contacts in China: a Markov model

This study evaluates the costs and cost-effectiveness of latent tuberculosis infection (LTBI) testing and preventive treatment (TPT) strategies among close contacts of active tuberculosis (ATB) patients in China using a Markov model, with the aim of informing the optimization of national TPT strategies. A Markov model was developed to evaluate the cost-effectiveness of LTBI testing with purified protein derivative (PPD), Mycobacterium TB antigen-based skin test (TBST), or interferon-gamma releas