Right ventricular (RV) dysfunction is a key predictor of outcomes in pulmonary hypertension (PH), substantially contributing to illness and death. As PH progresses, increased pulmonary vascular resistance places chronic pressure overload on the right ventricle. Initially, the right ventricle adapts through hypertrophic remodeling, thickening the heart wall to maintain cardiac output. Over time, this adaptive phase shifts to maladaptive remodeling, marked by RV dilation, fibrosis, stiffness, and
Advanced Molecular, Metabolic, and Imaging Approaches to Characterizing Right Ventricular Failure: A Scientific Statement From the American Heart Association
Soni Savai Pullamsetti·Sebastien Bonnet·Frances de Man·Vinicio A. de Jesus Perez·Anna R. Hemnes·MONICA MUKHERJEE·Laura Mercer-Rosa·Edda Spiekerkoetter·Khodr Tello·Rebecca R. Vanderpool
